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In a recent study under review at the Nature Portfolio journal and currently posted to Research Square* preprint server, researchers developed and assessed the immunogenicity of nanoparticles expressing spike trimers from coronaviruses (CoVs).
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https://www.news-medical.net/news/20221110/Mosaic-nanoparticles-displaying-spike-protein-trimers-from-different-coronaviruses-elicits-cross-reactive-protection.aspx
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