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Mitotic tethering enables inheritance of shattered micronuclear chromosomes - Nature.com
6/14/23 at 3:11pm
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Nature.com
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Chromothriptically produced pieces of a micronucleated chromosome are shown to be tethered together in mitosis by a protein complex consisting of MDC1, TOPBP1 and CIP2A, thus enabling their inheritance by a single daughter cell.
Science
Health Conditions
Biological Sciences
tethering
Nature.com Chromothriptically
CIP2A
MDC1
TOPBP1
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https://www.nature.com/articles/s41586-023-06216-z
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