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Ectopic expression of cytosolic DHODH uncouples de novo pyrimidine biosynthesis from mitochondrial electron transport - Nature
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2/17/26 at 4:36pm
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Cytosolic ScURA uncouples de novo pyrimidine synthesis from mitochondrial electron transport, and rescues pyrimidine production and cell proliferation under pharmacological or genetic mETC disruption.
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https://www.nature.com/articles/s42255-026-01454-7
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