A pan-cancer analysis of primary and metastatic tumors highlights the diversity of genetic immune escape mechanisms established during tumor evolution. The authors also present LILAC, a tool to characterize the HLA-I locus from whole-genome sequencing data.
According to a new study, artificial intelligence algorithms may be the key to identifying who is at the most risk of developing one of the most notoriously difficult cancers to diagnose early: pancreatic cancer.
After 600 rounds of selection, anaerobic snowflake yeast evolved to be macroscopic, becoming around 20,000 times larger (approximately mm scale) and about 10,000-fold more biophysically tough, while retaining a clonal multicellular life cycle.
The authors report a high-throughput combinatorial printing method capable of fabricating materials with compositional gradients at microscale spatial resolution, demonstrating a variety of high-throughput printing strategies and applications in combinatorial…
A loophole-free violation of Bell’s inequality with superconducting circuits shows that non-locality is a viable new resource in quantum information technology realized with superconducting circuits, promising many potential applications.
Lithographically patterned perovskite nanocrystal arrays were used to determine radiation vectors from X-rays to visible light and the emission colours of the nanoparticles was used to create images of three-dimensional objects and for phase-contrast imaging.
Salinity reconstructions show that Indian Ocean surface salinity increased during glacial periods and that the release of this water via the Agulhas Leakage during deglaciation can trigger abrupt changes in the Atlantic Meridional Overturning Circulation.
Complementary single-cell and single-nucleus transcriptomic analyses of Zea mays, Sorghum bicolor and Setaria viridis root cells provide insights into the evolution of cell types and gene modules that control key traits in these important crop species.
An international collaboration of researchers, including the Kavli Institute for the Physics and Mathematics of the Universe (Kavli IPMU) has succeeded in a proof-of-principle experiment to verify strong-field quantum electrodynamics with exotic atoms, by per…
Roscosmos cosmonauts Sergey Prokopyev and Dmitri Petelin conducted a spacewalk outside the International Space Station May 12 to assist in the deployment and...
In partnership with the European Space Agency, Swiss startup ClearSpace will test its space junk tech in 2026 for the 'first-ever mission to remove an existing derelict object from orbit.'
Researchers discovered they could reverse - or normalize - the malformed tumor vasculature by activating the stimulator of interferon genes (STING) pathway, a component of the immune system that plays an important role in protecting against pathogen infection…
The analysis of a 550-million-year-old fossil community found in the Australian outback shows that some of Earth's earliest animals were picky about where they lived, preferring the company of others like them.
Synthetic biologists engineer bacterial swarm patterns to visibly record environment, use deep learning to decode patterns; applications could range from monitoring environmental pollution to building living materials.
Mysore/Mysuru: The Indian Institute of Astrophysics (IIA) has achieved a significant milestone in the development of astronomy in the country by placing an order for the world’s first commercial LED Dome Planetarium with the Konika Minolta Inc. Consortium, Ja…
The Director of the Center of Excellence for Data-Driven Discovery at St. Jude Children’s Research Hospital was named a Fellow of the leading, 360-year-old Br
Mysore/Mysuru: The Cosmology Education and Research Training Centre (COSMOS), Mysuru, recently conducted an event at the Karnataka Police Academy Summer Camp, Nazarbad, for 1st to 10th grade students to educate them about the basics of astronomy. The event wa…
SpaceX's Axiom Space Ax-2 mission astronauts will grow induced pluripotent stem cells (iPSCs) on the International Space Station, marking the first time stem cells will be grown in space. They will test how limited gravity influences the development of heart …
Researchers at Sana Biotechnology, Inc., in California, have made a significant breakthrough in realizing the promise of stem cell therapy: stem cells that do not trigger an immune response from an immunologically incompatible donor.